Researchers from the Medical University of South Carolina have identified that antiseptic oral rinses will protect against jaw-bone loss. Different microbes in your gut, skin, and mouth can cause responses that can lead to responses that damage the bones in your mouth.
These researchers are trying to focus on a bigger issue to understand how certain bacteria can lead to conditions like gingivitis, tooth loss, loose teeth, and the deterioration of the bones in your mouth. Ultimately, the viruses, fungi, and bacteria in and on our bodies can affect our overall health which definitely includes our mouths.
To learn more about which specific bacteria can lead to bone loss and how these bacteria become activated check out the rest of our blog. Antiseptic oral rinses (mouthwash) can have a surprisingly massive benefit to preventing this bone loss (caused by Osteoclasts) than you probably knew about.
A collection of bacteria and fungi that can destroy our bones?
The researchers discovered that the alveolar bone which supports our teeth can be affected by Osteoclasts that are released by healthy microbes activating immune cells. Certain microbes can even impact the immune cells related to our bone health.
Chad M Novince the associate professor of Dental Medicine at the University of South Caroline said “The alveolar bone is different from other bone tissues due to its role in supporting the teeth.
“What is most fascinating to me is that we were able to show that the commensal oral microbiota modulates the communication between immune cells and bone cells, separate from other microbiota communities, that impact alveolar bone health.”
What techniques were used and how was testing done?
The team tested the bone marrow from the mandible of mice which allowed the researchers to perform in-depth studies within the alveolar bone. They also found a way to diminish the microbes within the mice’s oral cavity and used a sponge loaded with the oral rinse to treat the mice’s gingivitis.
The oral rinse ended up dampening the immune response and suppressing bone-resorbing osteoclast cells to reduce the effect of bone loss. The cells that were activated due to the presence of oral microbes (dendritic cells and CD4+ helper T-cells) and ended up helping the Osteoclasts destroy the Osteoclast cells were managed with the rinse.
How does an antiseptic mouthwash protect against bone loss?
The researchers explained how depleting the healthy oral microbiome protects against bone loss in preclinical models. It has become clear that reducing the burden of viruses, fungi, and bacteria in your mouth will limit the reaction that leads to Osteoclasts breaking down your jaw bone’s health.
According to Dr. Novince “We were able to show that the commensal oral microbiota influences alveolar bone homeostasis through osteoimmune mechanisms that are distinct from the systemic microbiome. “If we are able to suppress the healthy oral microbiome to lower levels, it could help protect from alveolar bone loss, even in a state of health.”
As research continues it’ll become more clear what types of microbes specifically lead to this immune reaction occurring that leads to bone loss. For now, the best course of action is to suppress oral microorganisms with antiseptic oral rinses. You may also want to consider getting regular fluoride treatments to manage oral bacteria. Healthline has rated the top 9 oral rinses for your mouth that you can see by clicking here: